Compound ID | 100

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Zempia (E-101)

Class: Antiseptic

Spectrum of activity: Gram-negative
Details of activity: E-101 solution represents the first-in-class topical myeloperoxidase-based microbicidal formulation applied directly to surgical wounds to prevent surgical-site infections (SSI).
Institute where first reported: Exoxemis, Inc., USA
Year first mentioned: 2008
Highest developmental phase: Phase 3 (NCT01297959)
Development status: Active
External links:
Citations:
  • http://aac.asm.org/content/58/8/4911.full
  • https://exoxemis.com/wp-content/uploads/2019/08/ECCMID_exoxemis_ESKAPE_eurofins_poster_v2big.pdf
  • https://iai.asm.org/content/87/7/e00261-19
  • https://exoxemis.com/technology/

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