Compound ID | 101

Lysostaphin

Class: Zinc metalloprotease (glycyl-glycine endopeptidase)

Spectrum of activity: Gram-positive
Details of activity: S. aureus catheter-associated and thigh infection models
Combined with other compounds: Yes
Propensity to select resistant mutants: No (demonstrated high resistance)
Institute where first reported: Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany
Year first mentioned: 1964
Development status: Experimental

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