Compound ID | 101
Lysostaphin
| Agent Type: | Natural product; Direct acting; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Cell wall degradation |
| Target Pathogen: | Active against Staphylococcus aureus |
| Combined with other compounds: | Yes |
| Propensity to select resistant mutants: | No (demonstrated high resistance) |
| Description: | A zinc metalloprotease (glycyl-glycine endopeptidase) from Staphylococcus simulans |
| Institute where first reported: | Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany |
| Year first mentioned: | 1964 |
| Development status: | Experimental |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/protein/P10547 |
| Citations: |
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