Compound ID | 1015

Update compound information

Meonomycin complex A

Class: Moenomycin

Spectrum of activity: Gram-positive
Details of activity: Direct inhibition of peptidoglycan glycosyltransferases.
Propensity to select resistant mutants: Yes
Year first mentioned: 1965
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 1282.15
Iso. SMILES: C[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)NC(=O)C)O[C@@H]3[C@H]([C@]([C@H](O[C@@H]3OP(=O)(O)OC[C@H](C(=O)O)OC/C=C(/C)\CCC=C(C)C)C(=O)N)(C)O)OC(=O)N)CO[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)NC(=O)C)O)O[C@H]5[C@@H]([C@H]([C@H]([C@H](O5)C(=O)N)O)O)O
InChI Key: RAPYBPXXZJZLIC-LMVGRRJQSA-N
Can. SMILES: CC(=CCC/C(=C\CO[C@H](COP(=O)(O)O[C@@H]1[C@@H]([C@H]([C@@](C)([C@@H](C(=O)N)O1)O)OC(=O)N)O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](C)O4)O[C@H]5[C@@H]([C@H]([C@H]([C@@H](C(=O)N)O5)O)O)O)O)NC(=O)C)O)NC(=O)C)C(=O)O)/C)C
InChI: InChI=1S/C49H80N5O32P/c1-16(2)9-8-10-17(3)11-12-74-23(42(68)69)15-76-87(72,73)86-47-37(38(85-48(52)70)49(7,71)39(84-47)41(51)67)83-44-25(54-20(6)57)28(60)35(22(79-44)14-75-45-32(64)29(61)26(58)21(13-55)78-45)81-43-24(53-19(5)56)27(59)34(18(4)77-43)80-46-33(65)30(62)31(63)36(82-46)40(50)66/h9,11,18,21-39,43-47,55,58-65,71H,8,10,12-15H2,1-7H3,(H2,50,66)(H2,51,67)(H2,52,70)(H,53,56)(H,54,57)(H,68,69)(H,72,73)/b17-11-/t18-,21-,22-,23-,24-,25-,26-,27-,28-,29+,30+,31-,32-,33-,34-,35-,36+,37-,38-,39-,43+,44+,45-,46-,47-,49+/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/24856361
Citation:

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