Compound ID | 1039

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Cefazaflur

Synonym(s): SKF 59962  |  SKF-59962  |  SKF59962

Class: Beta-lactam

Agent Type: Semisynthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Cell wall synthesis inhibitor. PBP inhibitor
Description: Cephalosporin-type
Institute where first reported: Smith Kline and French Laboratories
Year first mentioned: 1974
Development status: Experimental
Chemical structure(s):
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Molecular weight: 470.47
Iso. SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CSC(F)(F)F)SC2)C(=O)O
InChI Key: HGXLJRWXCXSEJO-GMSGAONNSA-N
Can. SMILES: CN1C(=NN=N1)SCC2=C(C(=O)O)N3C(=O)[C@H]([C@H]3SC2)NC(=O)CSC(F)(F)F
InChI: InChI=1S/C13H13F3N6O4S3/c1-21-12(18-19-20-21)28-3-5-2-27-10-7(9(24)22(10)8(5)11(25)26)17-6(23)4-29-13(14,15)16/h7,10H,2-4H2,1H3,(H,17,23)(H,25,26)/t7-,10-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/40240
Guide to Pharmacology: cefazaflur
Citation: https://doi.org/10.1128/aac.11.4.708

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