Pirbenicillin

Class: Beta-lactam (penicillin)

Spectrum of activity:	Gram-positive  &  Gram-negative
Propensity to select resistant mutants:	Yes
Institute where first reported:	Pfizer Inc
Year first mentioned:	1975
Highest developmental phase:	Preclinical
Reason Dropped:	"disappointing clinical results"-only found mention of this once however.

Chemical structure(s):
Canonical SMILES:	CC1(C)[C@H](C(=O)O)N2C(=O)[C@H]([C@H]2S1)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)CN=C(C4=CC=NC=C4)N
Isomeric SMILES:	CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)CN=C(C4=CC=NC=C4)N)C(=O)O)C
InChI:	InChI=1S/C24H26N6O5S/c1-24(2)18(23(34)35)30-21(33)17(22(30)36-24)29-20(32)16(13-6-4-3-5-7-13)28-15(31)12-27-19(25)14-8-10-26-11-9-14/h3-11,16-18,22H,12H2,1-2H3,(H2,25,27)(H,28,31)(H,29,32)(H,34,35)/t16-,17-,18+,22-/m1/s1
InChI Key:	WRFCGBVLTRJBKN-QSNWEANLSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/9871712

External links:
Guide to Pharmacology:	pirbenicillin
Citation:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC429777/