Compound ID | 1052
Class: Aminoglycoside
Spectrum of activity: | Gram-negative |
Details of activity: | DNA Synthesis inhibitor |
Institute where first reported: | The UpJohn Company |
Year first mentioned: | 1976 |
Highest developmental phase: | Preclinical |
Development status: | Inactive |
Reason Dropped: | "lack of clinical promise" |
Chemical structure(s): | |
Canonical SMILES: | CC(C(C(=O)O)NC(=O)C(CC1=CN=CN1)NC)NC(CC2=CN=CN2)C(=O)O |
Isomeric SMILES: | CC(C(C(=O)O)NC(=O)C(CC1=CN=CN1)NC)NC(CC2=CN=CN2)C(=O)O |
InChI: | InChI=1S/C17H25N7O5/c1-9(23-13(16(26)27)4-11-6-20-8-22-11)14(17(28)29)24-15(25)12(18-2)3-10-5-19-7-21-10/h5-9,12-14,18,23H,3-4H2,1-2H3,(H,19,21)(H,20,22)(H,24,25)(H,26,27)(H,28,29) |
InChI Key: | LUOBEJSTJAVJPL-UHFFFAOYSA-N |
Structure link: | https://pubchem.ncbi.nlm.nih.gov/compound/10409115 |
External links: | |
Guide to Pharmacology: | feldamycin |
Citation: | https://www.ncbi.nlm.nih.gov/pubmed/994320 |