Compound ID | 1052

Feldamycin

Class: Aminoglycoside

Spectrum of activity: Gram-negative
Details of activity: DNA Synthesis inhibitor
Institute where first reported: The UpJohn Company
Year first mentioned: 1976
Highest developmental phase: Preclinical
Development status: Inactive
Reason Dropped: "lack of clinical promise"
Chemical structure(s):
Canonical SMILES: CC(C(C(=O)O)NC(=O)C(CC1=CN=CN1)NC)NC(CC2=CN=CN2)C(=O)O
Isomeric SMILES: CC(C(C(=O)O)NC(=O)C(CC1=CN=CN1)NC)NC(CC2=CN=CN2)C(=O)O
InChI: InChI=1S/C17H25N7O5/c1-9(23-13(16(26)27)4-11-6-20-8-22-11)14(17(28)29)24-15(25)12(18-2)3-10-5-19-7-21-10/h5-9,12-14,18,23H,3-4H2,1-2H3,(H,19,21)(H,20,22)(H,24,25)(H,26,27)(H,28,29)
InChI Key: LUOBEJSTJAVJPL-UHFFFAOYSA-N
Structure link: https://pubchem.ncbi.nlm.nih.gov/compound/10409115
External links:
Guide to Pharmacology: feldamycin
Citation: https://www.ncbi.nlm.nih.gov/pubmed/994320

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