Cefsulodin

Synonym(s): CGP 7174/E

Class: Beta-lactam (cephalosporin)

Spectrum of activity:	Gram-negative
Details of activity:	Active against Pseudomonas. Mainly used for research purposes in selective media.
Description:	Tosch, W., et al. "In vitro characterization of CGP 7174/E, a Cephalosporin active against Pseudomonas." Current chemotherapy 2 (1978): 843-844. 10th ICAAC p. 843
Institute where first reported:	Takeda Pharmaceuticals
Year first mentioned:	1977
Highest developmental phase:	Phase 4
Development status:	Inactive
Reason Dropped:	Poor stability.

Chemical structure(s):
Canonical SMILES:	C1=CC=C(C=C1)[C@H](C(=O)N[C@@H]2C(=O)N3C(=C(C[N+]4=CC=C(C=C4)C(=O)N)CS[C@H]23)C(=O)[O-])S(=O)(=O)O
Isomeric SMILES:	C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)S(=O)(=O)O)C(=O)[O-])C[N+]4=CC=C(C=C4)C(=O)N
InChI:	InChI=1S/C22H20N4O8S2/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34)/t15-,17-,21-/m1/s1
InChI Key:	SYLKGLMBLAAGSC-QLVMHMETSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/656575

External links:
Guide to Pharmacology:	cefsulodin