Compound ID | 1066

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Alafosfalin

Class: Phosphonodipeptide

Spectrum of activity: Gram-negative
Propensity to select resistant mutants: Yes
Institute where first reported: Roche Products Limitted
Year first mentioned: 1979
Highest developmental phase: Preclinical
Development status: Inactive
Reason Dropped: Therapuetic usefulness limitted by selection of resistant mutants
Chemical structure(s):
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Molecular weight: 196.14
Iso. SMILES: CC(C(=O)NC(C)P(=O)(O)O)N
InChI Key: BHAYDBSYOBONRV-UHFFFAOYSA-N
Can. SMILES: CC(C(=O)NC(C)P(=O)(O)O)N
InChI: InChI=1S/C5H13N2O4P/c1-3(6)5(8)7-4(2)12(9,10)11/h3-4H,6H2,1-2H3,(H,7,8)(H2,9,10,11)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/71957
Guide to Pharmacology: alafosfalin
Citations:
  • https://www.ncbi.nlm.nih.gov/pubmed/116591

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