E-0702 antibiotic

Class: Beta-lactam

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Strong anti-pseudomonal activity.
Institute where first reported:	Eisai Co
Year first mentioned:	1981
Development status:	Inactive
Reason Dropped:	Presumably due to development of resistance and competition

Chemical structure(s):
Canonical SMILES:	C1=C(C=CC(=C1)O)C(C(=O)NC2C(=O)N3C(=C(CSC23)CSC4=NN=NN4CC(=O)O)C(=O)O)NC(=O)C5=COC6=C(C=C(C(=C6)O)O)C5=O.[Na+]
Isomeric SMILES:	C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)NC(=O)C4=COC5=CC(=C(C=C5C4=O)O)O)C(=O)O)CSC6=NN=NN6CC(=O)O.[Na+]
InChI:	InChI=1S/C29H23N7O12S2.Na/c37-13-3-1-11(2-4-13)20(30-24(43)15-8-48-18-6-17(39)16(38)5-14(18)23(15)42)25(44)31-21-26(45)36-22(28(46)47)12(9-49-27(21)36)10-50-29-32-33-34-35(29)7-19(40)41;/h1-6,8,20-21,27,37-39H,7,9-10H2,(H,30,43)(H,31,44)(H,40,41)(H,46,47);/q;+1
InChI Key:	KBEFTEIZDFHDJP-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/5748775

External links:
Guide to Pharmacology:	E-0702
Citation:	http://aac.asm.org/content/22/2/181.short