Compound ID | 1088

Update compound information

Cefatiolene

Synonym(s): Ceftiolene  |  RP 42980  |  42980RP

Class: Beta-lactam

Agent Type: Semisynthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Cell wall synthesis inhibitor
Institute where first reported: Rhône-Poulenc
Year first mentioned: 1981
Development status: Experimental
Chemical structure(s):
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Molecular weight: 594.6
Iso. SMILES: CO/N=C(\C1=CSC(=N1)N)/C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)/C=C/SC4=NNC(=O)C(=O)N4CC=O)C(=O)O
InChI Key: WJXAHFZIHLTPFR-RRBRMZJWSA-N
Can. SMILES: CO/N=C(\C1=CSC(=N1)N)/C(=O)N[C@@H]2C(=O)N3C(=C(/C=C/SC4=NNC(=O)C(=O)N4CC=O)CS[C@H]23)C(=O)O
InChI: InChI=1S/C20H18N8O8S3/c1-36-26-10(9-7-39-19(21)22-9)13(30)23-11-15(32)28-12(18(34)35)8(6-38-17(11)28)2-5-37-20-25-24-14(31)16(33)27(20)3-4-29/h2,4-5,7,11,17H,3,6H2,1H3,(H2,21,22)(H,23,30)(H,24,31)(H,34,35)/b5-2+,26-10+/t11-,17-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6436117
Guide to Pharmacology: ceftiolene
Citations:
  • https://www.ncbi.nlm.nih.gov/pubmed/6312397
  • https://doi.org/10.1093/jac/14.6.581

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