Cefpimizole

Synonym(s): U 63196E

Class: Beta-lactam

Spectrum of activity:	Gram-positive  &  Gram-negative
Description:	Kato, N., et al. "In vitro and in vivo antibacterial activities of AC-1370, a new third generation Cephalosporin." 22nd ICCAC. 1982. 205.
Institute where first reported:	The UpJohn Company
Year first mentioned:	1982
Development status:	Inactive
Reason Dropped:	Similar spectrum to other Cephalosporins but poor time in blood

Chemical structure(s):
Canonical SMILES:	C1=CC=C(C=C1)[C@H](C(=O)N[C@@H]2C(=O)N3C(=C(C[N+]4=CC=C(C=C4)CCS(=O)(=O)[O-])CS[C@H]23)C(=O)O)NC(=O)C5=C(C(=O)O)NC=N5
Isomeric SMILES:	C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)C4=C(NC=N4)C(=O)O)C(=O)O)C[N+]5=CC=C(C=C5)CCS(=O)(=O)[O-]
InChI:	InChI=1S/C28H26N6O10S2/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44)/t18-,21-,26-/m1/s1
InChI Key:	LNZMRLHZGOBKAN-KAWPREARSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/68597

External links:
Guide to Pharmacology:	cefpimizole
Citation:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC175025/pdf/aac00101-0064.pdf