Compound ID | 110

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Benzimidazole-Based FABI inhibitor 8

Class: Fatty acid synthesis inhibitor (FabI inhibitor)

Spectrum of activity: Gram-positive
Details of activity: Inhibits FabI, which determines the completing of each cycle of elongation in the fatty acid synthesis. Designed for Francisella tularensis.
Institute where first reported: University of Illinois at Chicago, USA
Year first mentioned: 2014
Development status: Experimental
External links:
Citations:
  • http://pubs.acs.org/doi/abs/10.1021/acsinfecdis.6b00123
  • https://www.sciencedirect.com/science/article/pii/S0960894X15000608?casa_token=VjSLxsY8VmQAAAAA:XMy3jLRPqJHWbnzP7DAK0IZsrrVdmFF5lRxEfCXnXHrUSXEoXb5Eo-THt9jy8dDdrCr8CyKjUAw
  • http://www.ncbi.nlm.nih.gov/pubmed/22642319
  • https://pubs.acs.org/doi/10.1021/jm300489v

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