Compound ID | 1100

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Sch 29482

Class: Beta-lactam

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against gram - and + bacteria with the exception of Pseudomonas
Description: Kayser. F, H. "Sch 29482: Laboratory evaluation of a new penem antibiotic . [abstract no. 739]." Programs and abstracts of the 21St Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago , Illinois. American Society for Microbiology. 1981.
Institute where first reported: Schering Corporation
Year first mentioned: 1982
Highest developmental phase: Phase 1
Development status: Inactive
Reason Dropped: Poor efficacy compared with competitors
Chemical structure(s):
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Molecular weight: 275.35
Iso. SMILES: CCSC1=C(N2[C@H](S1)[C@H](C2=O)[C@@H](C)O)C(=O)O
InChI Key: LDVDKTLZRGWFID-GLDDHUGJSA-N
Can. SMILES: CCSC1=C(C(=O)O)N2C(=O)[C@H]([C@@H](C)O)[C@H]2S1
InChI: InChI=1S/C10H13NO4S2/c1-3-16-10-6(9(14)15)11-7(13)5(4(2)12)8(11)17-10/h4-5,8,12H,3H2,1-2H3,(H,14,15)/t4-,5+,8-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/13120881
Guide to Pharmacology: Sch 29482
Citations:
  • https://academic.oup.com/jac/article-abstract/9/suppl_C/49/740655/Antibacterial-activity-of-an-oral-penem-Sch-29482?redirectedFrom=fulltext

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