Sch 29482

Class: Beta-lactam

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Active against gram - and + bacteria with the exception of Pseudomonas
Description:	Kayser. F, H. "Sch 29482: Laboratory evaluation of a new penem antibiotic . [abstract no. 739]." Programs and abstracts of the 21St Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago , Illinois. American Society for Microbiology. 1981.
Institute where first reported:	Schering Corporation
Year first mentioned:	1982
Highest developmental phase:	Phase 1
Development status:	Inactive
Reason Dropped:	Poor efficacy compared with competitors

Chemical structure(s):
Canonical SMILES:	CCSC1=C(C(=O)O)N2C(=O)[C@H]([C@@H](C)O)[C@H]2S1
Isomeric SMILES:	CCSC1=C(N2[C@H](S1)[C@H](C2=O)[C@@H](C)O)C(=O)O
InChI:	InChI=1S/C10H13NO4S2/c1-3-16-10-6(9(14)15)11-7(13)5(4(2)12)8(11)17-10/h4-5,8,12H,3H2,1-2H3,(H,14,15)/t4-,5+,8-/m1/s1
InChI Key:	LDVDKTLZRGWFID-GLDDHUGJSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/13120881

External links:
Guide to Pharmacology:	Sch 29482
Citation:	https://academic.oup.com/jac/article-abstract/9/suppl_C/49/740655/Antibacterial-activity-of-an-oral-penem-Sch-29482?redirectedFrom=fulltext