Compound ID | 1109
Class: Beta-lactam
Spectrum of activity: | Gram-negative |
Details of activity: | Targetted to cell wall biosynthesis with limitted efficacy |
Institute where first reported: | Smith Kline and French Laboratories |
Year first mentioned: | 1984 |
Highest developmental phase: | Preclinical |
Development status: | Inactive |
Chemical structure(s): | |
Canonical SMILES: | C1=C(C=CC(=C1)OCC[C@H](C(=O)O)N)/C(=N/O)/C(=O)N[C@H]2CN([C@H](C3=CC=C(C(=C3)Cl)O)C(=O)O)C2=O |
Isomeric SMILES: | C1[C@@H](C(=O)N1[C@H](C2=CC(=C(C=C2)O)Cl)C(=O)O)NC(=O)/C(=N\O)/C3=CC=C(C=C3)OCC[C@H](C(=O)O)N |
InChI: | InChI=1S/C23H23ClN4O9/c24-14-9-12(3-6-17(14)29)19(23(34)35)28-10-16(21(28)31)26-20(30)18(27-36)11-1-4-13(5-2-11)37-8-7-15(25)22(32)33/h1-6,9,15-16,19,29,36H,7-8,10,25H2,(H,26,30)(H,32,33)(H,34,35)/b27-18-/t15-,16+,19-/m1/s1 |
InChI Key: | UMDAIHWMUXNVSB-GUZYLKIGSA-N |
External links: | |
Structure link: | https://pubchem.ncbi.nlm.nih.gov/compound/6400675 |
Guide to Pharmacology: | chlorocardicin |
Citation: | https://www.ncbi.nlm.nih.gov/pubmed/3922933 |