Compound ID | 1119

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Ibafloxacin

Synonym(s): S-25930  |  S 25930  |  S25930

Class: Quinolone

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: DNA synthesis inhibitor
Propensity to select resistant mutants: Yes
Description: KARWOWSKI, JAMES P., et al. "Spenolimycin, a new spectinomycin-type antibiotic. I. Discovery, taxonomy and fermentation." The Journal of antibiotics 37.12 (1984): 1513-1518.
Institute where first reported: Riker Labs
Year first mentioned: 1984
Highest development stage: Approved for veterinary use
Development status: Approved
Chemical structure(s):
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Molecular weight: 275.28
Iso. SMILES: CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2C)F)C(=O)O
InChI Key: DXKRGNXUIRKXNR-UHFFFAOYSA-N
Can. SMILES: CC1CCC2=C(C)C(=CC3=C2N1C=C(C3=O)C(=O)O)F
InChI: InChI=1S/C15H14FNO3/c1-7-3-4-9-8(2)12(16)5-10-13(9)17(7)6-11(14(10)18)15(19)20/h5-7H,3-4H2,1-2H3,(H,19,20)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/71186
Guide to Pharmacology: ibafloxacin
Citations:
  • https://doi.org/10.1128/aac.31.1.102
  • https://doi.org/10.1046/j.1365-2885.2002.00361.x
  • https://doi.org/10.1007/BF02017786

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