Compound ID | 1121

3’-quaternary ammonium Cephalosporins

Class: Beta-lactam (cephalosporin)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Showed excellent broad spectrum activity to gram - and + bacteria. Some of which showed cardiotoxic effects in a rat model.
Description: R. F. Brown., et al. "Microbiological and Pharmacological properties of a new series of 3'-quaternary ammonium Cephalosporins [Abstract 365]" Program and Abstracts of the 25th Intersci. Conf. on Antimicrob. Agents Chemother. No. 1141.
Institute where first reported: The Lilly Research Laboratories
Year first mentioned: 1984
Highest developmental phase: Preclinical
Development status: Inactive
External links:
Citation:

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