Compound ID | 1135

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DZ-2640

Class: Beta-lactam (carbapenem)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Broad spectrum against gram + and - bacteria. Good oral absporbtion
Description: Nishi, T., et al. "DZ-2640, a new oral carbapenem antibiotic, 1: structure activity relationships and in vitro activity." Program and Abstracts of the Thirty-Fifth Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco. 1995.
Institute where first reported: Daiichi Seiyaku Co
Year first mentioned: 1995
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 463.55
Iso. SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3CC4=NC=CN4C3)C(=O)OCOC(=O)C(C)(C)C)[C@@H](C)O
InChI Key: SVIXKYNOOFZUFA-CNRIWFPOSA-N
Can. SMILES: C[C@@H]1[C@@H]2[C@@H]([C@@H](C)O)C(=O)N2C(=C1S[C@H]3CC4=NC=CN4C3)C(=O)OCOC(=O)C(C)(C)C
InChI: InChI=1S/C22H29N3O6S/c1-11-16-15(12(2)26)19(27)25(16)17(20(28)30-10-31-21(29)22(3,4)5)18(11)32-13-8-14-23-6-7-24(14)9-13/h6-7,11-13,15-16,26H,8-10H2,1-5H3/t11-,12-,13+,15-,16-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9804440
Citation:

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