Compound ID | 1138

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MEN 10700

Class: Beta-lactam (penem)

Details of activity: Showed promisingly high activity against the Pneumococcus
Description: Fontana, R., et al. "MEN 10700, a new penem antibiotic: in-vitro activity and its correlation with beta-lactamase stability, PBP affinity and diffusion through the bacterial cell wall." Journal of Antimicrobial Chemotherapy 41.5 (1998): 513-525.
Institute where first reported: Menarini
Year first mentioned: 1998
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 315.35
Iso. SMILES: C[C@H]([C@@H]1C2N(C1=O)C(=C(S2)CN(C)CC(=O)N)C(=O)O)O
InChI Key: HKHRWODVCOCCIC-UCZFRPJKSA-N
Can. SMILES: C[C@H]([C@H]1C(=O)N2C(=C(CN(C)CC(=O)N)SC12)C(=O)O)O
InChI: InChI=1S/C12H17N3O5S/c1-5(16)8-10(18)15-9(12(19)20)6(21-11(8)15)3-14(2)4-7(13)17/h5,8,11,16H,3-4H2,1-2H3,(H2,13,17)(H,19,20)/t5-,8+,11?/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/44367961
Citation:

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