levopropylcillin

Synonym(s): L-Propicillin  |  BRL-284

Class: Beta-lactam (penicillin)

Spectrum of activity:	Gram-positive
Details of activity:	Active against Staphylococci but not stable to penicillinase
Description:	Godzeski, C, W et al. "An In Vitro Examination of Levopropylcillin" Program and Abstracts of the interscience science Conference on Antimicrobial Agents and Chemotherapy. 1961.
Institute where first reported:	Eli Lilly
Year first mentioned:	1961
Highest developmental phase:	Preclinical
Development status:	Inactive
Reason Dropped:	Resistance and competition from competing drugs

Chemical structure(s):
Canonical SMILES:	CC[C@@H](C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12)OC3=CC=CC=C3
Isomeric SMILES:	CC[C@@H](C(=O)N[C@H]1[C@@H]2N(C1=O)[C@H](C(S2)(C)C)C(=O)O)OC3=CC=CC=C3
InChI:	InChI=1S/C18H22N2O5S/c1-4-11(25-10-8-6-5-7-9-10)14(21)19-12-15(22)20-13(17(23)24)18(2,3)26-16(12)20/h5-9,11-13,16H,4H2,1-3H3,(H,19,21)(H,23,24)/t11-,12+,13-,16+/m0/s1
InChI Key:	HOCWPKXKMNXINF-RSUWNVLCSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/172994

External links:
Guide to Pharmacology:	levopropicillin