Compound ID | 1161

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MSD-819

Spectrum of activity: Gram-positive
Details of activity: Membrane-acting, not selective; low activity against some gram-positive and Gram-negative bacteria
Description: Stapley, E.O "Antibiotic MSD-819. Microbial production and biological charecteristics" Program and Abstracts of the interscience science Conference on Antimicrobial Agents and Chemotherapy. 1968.
Institute where first reported: Merck Sharp and Dohme
Year first mentioned: 1968
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 240.6
Iso. SMILES: C1=CC2=C(C=C1Cl)[N+](=O)C=C(N2[O-])C(=O)O
InChI Key: OREKRDMCWBYLFR-UHFFFAOYSA-N
Can. SMILES: C1=C(C=C2C(=C1)N(C(=C[N+]2=O)C(=O)O)[O-])Cl
InChI: InChI=1S/C9H5ClN2O4/c10-5-1-2-6-7(3-5)11(15)4-8(9(13)14)12(6)16/h1-4H,(H,13,14)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/54690348
Citations:
  • https://eprints.whiterose.ac.uk/106581/
  • https://pubmed.ncbi.nlm.nih.gov/5735369/
  • https://pubmed.ncbi.nlm.nih.gov/5735368/

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