Compound ID | 1163

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BL-S 217

Class: Beta-lactam (cephalosporin, first generation)

Spectrum of activity: Gram-positive
Details of activity: Active against Gram-positive bacteria
Description: Buck, R.E et al "BL-S 217, a New Semi-synthetic Cephalosporin" Program and Abstracts of the interscience science Conference on Antimicrobial Agents and Chemotherapy. 1971.
Institute where first reported: Bristol Myers Squibb
Year first mentioned: 1971
Highest development stage: Preclinical
Development status: Inactive
Reason dropped: Resistance and competition from competing drugs
Chemical structure(s):
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Molecular weight: 438.5
Iso. SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)CSC3=CC=[N+](C=C3)C)SC1)C(=O)O
InChI Key: MVCWQSBQUMRYDD-RHSMWYFYSA-O
Can. SMILES: CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@H]([C@H]2SC1)NC(=O)CSC3=CC=[N+](C)C=C3
InChI: InChI=1S/C18H19N3O6S2/c1-10(22)27-7-11-8-29-17-14(16(24)21(17)15(11)18(25)26)19-13(23)9-28-12-3-5-20(2)6-4-12/h3-6,14,17H,7-9H2,1-2H3,(H-,19,23,25,26)/p+1/t14-,17-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/191168
Citation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC444167/

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