Compound ID | 1164

Update compound information

Maridomycin

Synonym(s): LS-87912, mono, di, and tri acyl derivatives

Class: Macrolide

Spectrum of activity: Gram-positive
Details of activity: Active against Gram-positive bacteria, identical to Josamycin
Description: Higashide, E et al "Maridomycin, a New Macrolide Antibiotic" Program and Abstracts of the interscience science Conference on Antimicrobial Agents and Chemotherapy. 1971.
Institute where first reported: Takeda Pharmaceuticals
Year first mentioned: 1971
Highest development stage: Preclinical
Development status: Inactive
Chemical structure(s):
Click here for structure editor
Molecular weight: 829.97
Iso. SMILES: CCC(=O)OC1CC(=O)OC(CC2C(O2)/C=C/C(C(CC(C(C1OC)OC3C(C(C(C(O3)C)OC4CC(C(C(O4)C)OC(=O)CC)(C)O)N(C)C)O)CC=O)C)O)C
InChI Key: FFXJTOKFQATYBI-BUHFOSPRSA-N
Can. SMILES: CCC(=O)OC1CC(=O)OC(C)CC2C(/C=C/C(C(C)CC(CC=O)C(C1OC)OC3C(C(C(C(C)O3)OC4CC(C)(C(C(C)O4)OC(=O)CC)O)N(C)C)O)O)O2
InChI: InChI=1S/C41H67NO16/c1-11-30(45)55-29-19-32(47)51-22(4)18-28-27(54-28)14-13-26(44)21(3)17-25(15-16-43)37(38(29)50-10)58-40-35(48)34(42(8)9)36(23(5)53-40)57-33-20-41(7,49)39(24(6)52-33)56-31(46)12-2/h13-14,16,21-29,33-40,44,48-49H,11-12,15,17-20H2,1-10H3/b14-13+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6436045
Guide to Pharmacology: maridomycin
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC444519/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC444520/

  • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.