Compound ID | 1172

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Pyrroxamycin

Synonym(s): Fioxapyrrolomycin  |  LL-F42248 alpha  |  AL-R2081

Class: Pyrrolomycin

Spectrum of activity: Gram-positive
Details of activity: Structural similar to pyrrolomycin. Active against Gram-positive bacteria
Description: Goodman, J, J et al "LL-F42248, a New Chlorinated Pyrolle Antibiotic" Program and Abstracts of the interscience science Conference on Antimicro0bial Agents and Chemotherapy. 1986.
Institute where first reported: American Cyanamid
Year first mentioned: 1986
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 384
Iso. SMILES: C1O[C@@H](C2=C(O1)C(=CC(=C2)Cl)Cl)C3=C(C(=C(N3)Cl)Cl)[N+](=O)[O-]
InChI Key: CUPRKSFMHRXAFA-NSHDSACASA-N
Can. SMILES: C1=C2C(=C(C=C1Cl)Cl)OCO[C@@H]2C3=C(C(=C(Cl)N3)Cl)[N+](=O)[O-]
InChI: InChI=1S/C12H6Cl4N2O4/c13-4-1-5-10(6(14)2-4)21-3-22-11(5)8-9(18(19)20)7(15)12(16)17-8/h1-2,11,17H,3H2/t11-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/129138
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/40/7/40_7_961/_pdf/-char/en
  • https://www.jstage.jst.go.jp/article/antibiotics1968/40/2/40_2_233/_pdf/-char/en

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