Compound ID | 1189
CB-618
Class: Beta-lactamase inhibitor
| Spectrum of activity: | Gram-negative |
| Details of activity: | Active against several Enterobacteriaceae producing different b-lactamase enzymes in combination with meripenem |
| Combined with other compounds: | Meripenem |
| Description: | VanScoy. B., Rubino, C., McCauley.J., Conde. H., Bhavnani. S., Friedrich. L., Alexander. D., Ambrose. P. "Pharmacokinetics-Pharmacodynamics (PK-PD) of CB-618, a Novel β-Lactamase Inhibitor, in Combination with Meropenem (MER) in an In Vitro Infection Model " Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy. 2015. |
| Institute where first reported: | TAXIS Pharmaceuticals |
| Year first mentioned: | 2015 |
| Highest developmental phase: | Phase 1 |
| Development status: | Active |
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