Compound ID | 1193
ACT-292706
Synonym(s): ACT292706 | ACT 292706
Class: Small molecule antibacterial agent
| Agent Type: | Synthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | DNA synthesis inhibitor. Bacterial topoisomerase inhibitor |
| Target Pathogen: | Active against streptococci and staphylococci |
| Description: | Lepak. A., Seiler. P., Surivet. J., Ritz. D., Kohl. C and Ander. A. "Pharmacokinetic/pharmacodynamic Evaluation of a Novel Topo-isomerase Inhibitor, ACT-29270, in a Murine Thigh and Lung Infection Model Against Staphylococcus aureus (sa) and Streptococcus pneumoniae (spn) " Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy. 2015. |
| Institute where first reported: | GlaxoSmithKline |
| Year first mentioned: | 2015 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
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