Compound ID | 1193

Update compound information

ACT-292706

Class: Bacterial topoisomerase inhibitor

Spectrum of activity: Gram-positive
Details of activity: Topoisomerase inhibitor with activity against steptococci and staphylococci
Description: Lepak. A., Seiler. P., Surivet. J., Ritz. D., Kohl. C and Ander. A. "Pharmacokinetic/pharmacodynamic Evaluation of a Novel Topo-isomerase Inhibitor, ACT-29270, in a Murine Thigh and Lung Infection Model Against Staphylococcus aureus (sa) and Streptococcus pneumoniae (spn) " Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy. 2015.
Institute where first reported: GlaxoSmithKline
Year first mentioned: 2015
Highest developmental phase: Preclinical
Development status: Active
External links:
Citations:
  • http://www.abstractsonline.com/plan/ViewAbstract.aspx?mID=3798&sKey=066fe91c-1dff-48d2-a97e-9d682ce3a71c&cKey=5d931c2d-ce42-4a88-ac0d-b9eac346ff59&mKey=7a574a80-eab1-4b50-b343-4695df14907e
  • https://journals.asm.org/doi/10.1128/aac.00363-16

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