Compound ID | 1197
HT-06
Class: Beta-lactam
| Agent Type: | Semisynthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Cell wall synthesis inhibitor |
| Target Pathogen: | Active against multidrug-resistant Acinetobacter baumannii |
| Combined with other compounds: | Sulbactam |
| Description: | A cephalosporin/ carbacephem [loracarbef-conjugate]; Yin. Y., Miller. P., Mollmann. U., Claypool. W., Schroeder. V., Wolter. W., Suckhow. M., Miller. M. "HT-06, a Bis Catechol-loracarbef Conjugate, with Sulbactam is Highly Active Against Drug Resistant Strains of Acinetobacter baumannii " Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy. 2015. |
| Institute where first reported: | The Medicines Company |
| Year first mentioned: | 2015 |
| Development status: | Experimental |
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