Compound ID | 1198

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RPX7381

Class: Beta-lactamase inhibitor (carbapenemase inhibitor)

Spectrum of activity: Gram-negative
Details of activity: Data demonstrated inhibition of carbapenemases in E. coli without displaying MICs.
Description: Lomovskaya. O., Tsivkovski. R."Biochemical Characterization of the Broad-Spectrum Carbapenemase Inhibitor (BCI) RPX7381 " Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy. 2015.
Institute where first reported: Paratek Pharmaceuticals
Year first mentioned: 2015
Highest developmental phase: Preclinical
Development status: Active
External links:
Citation: http://www.abstractsonline.com/plan/ViewAbstract.aspx?mID=3798&sKey=a9c3fb9c-e914-46aa-8248-7995700b69fe&cKey=18626076-8d55-4297-a7aa-df0000c053c6&mKey=7a574a80-eab1-4b50-b343-4695df14907e

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