Compound ID | 1201

Update compound information

CA-1049

Synonym(s): CA1049  |  CA 1049

Class: Polymyxin

Agent Type: Semisynthetic; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: Membrane-active agent. Binds to the lipid A component of the lipopolysaccharide to disrupt the physical integrity of the phospholipid bilayer of the inner membrane
Description: Polymixin B Derivative
Institute where first reported: Univ. of Milano-Bicocca
Year first mentioned: 2015
Development status: Experimental
External links:
Structure link: https://doi.org/10.1038/ja.2016.146
Citations:
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC6780002/
  • https://doi.org/10.1038/ja.2016.146
  • http://www.abstractsonline.com/plan/ViewAbstract.aspx?mID=3798&sKey=e9282513-65dd-4571-8dd4-cb67481cbcdb&cKey=6352cd78-59d5-4a66-9854-01c8c2a345a0&mKey=7a574a80-eab1-4b50-b343-4695df14907e

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