Compound ID | 1203

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P300847

Class: Pyridone

Spectrum of activity: Gram-negative
Details of activity: Active against drug resistant Neisseria gonorrhoeae
Propensity to select resistant mutants: Y (same order as ciprofloxacin)
Description: Narasimhan. J., Peddi. S., Letinski. S., Jung. S., Wang. J., Gerasyuto. A., Arnold. M., Hedrick. J., Dumble. M., Karp. G., Branstorm. A."Mode of Action of Novel Fused 2-Pyridones Against Neisseria gonorrhoeae " Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy. 2015.
Institute where first reported: Hsiri Therapeutics
Year first mentioned: 2015
Highest developmental phase: Preclinical
Development status: Active
External links:
Citation: http://www.abstractsonline.com/plan/ViewAbstract.aspx?mID=3798&sKey=8a05e7b3-9d7b-4399-8677-79e7be200add&cKey=c5c339b1-b106-4bb3-ae24-ec19dd680198&mKey=7a574a80-eab1-4b50-b343-4695df14907e

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