Compound ID | 1204

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HT-10

Class: Lipopeptide-siderophore conjugate

Spectrum of activity: Gram-negative
Details of activity: Daptomycin conjugated to A. baumannii's natural siderophore (fimsbactin).
Description: Ghosh. M., Miller. P., Mollmann. U., Claypool. W., Schroeder. V., Wolter. W., Suckhow. M., Miller. M."Siderophore Substitution on Daptomycin Confers Anti-Acinetobacter baumannii Bacterial Activity Both in vitro and in vivo " Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy. 2015.
Institute where first reported: Wockhardt
Year first mentioned: 2015
Highest developmental phase: Preclinical
Development status: Active
External links:
Citation: http://www.abstractsonline.com/plan/ViewAbstract.aspx?mID=3798&sKey=8a05e7b3-9d7b-4399-8677-79e7be200add&cKey=9fd61b01-94a3-42e2-8755-f1025b7c843d&mKey=7a574a80-eab1-4b50-b343-4695df14907e

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