Compound ID | 1208
APY281
Synonym(s): APY-281 | APY 281
Class: Small molecule antibacterial agent
| Agent Type: | Synthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | RNA synthesis inhibitor. RNA polymerase inhibitor; binding site distinct to rifampin and fidaxomicin |
| Combined with other compounds: | yes |
| Propensity to select resistant mutants: | yes |
| Description: | An aryl myxopyronin-type antibiotic |
| Institute where first reported: | Rutgers University |
| Year first mentioned: | 2016 |
| Development status: | Experimental |
| External links: | |
| Citations: |
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| Patent: | US11685723B2 |
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