Compound ID | 1210

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Avarofloxacin

Synonym(s): JNJ-Q2

Class: Fluoroquinolone

Spectrum of activity: Gram-positive
Details of activity: Active against methicillin-resistant Staphylococcus aureus
Description: Broad Spectrum In Vitro Activity of JNJ-Q2, a New Fluoroquinolone. F1-2033. 48th Annu. Intersci. Conf. Antimicrob. Agents Chemother. (ICAAC)-Infect. Dis. Soc. Am. (IDSA) 46th Annu. Meet. American Society for Microbiology and Infectious Diseases Society of America, Washington, DC. By: Foleno, B
Institute where first reported: Johnson & Johnson, Melinta Therapeutics Inc.
Year first mentioned: 2008
Highest developmental phase: Phase 2 (NCT01128530)
Development status: Active
Chemical structure(s):
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Molecular weight: 419.42
Iso. SMILES: COC1=C2C(=CC(=C1N3CCC/C(=C(/CN)\F)/C3)F)C(=O)C(=CN2C4CC4)C(=O)O
InChI Key: VMKVDAAFMQKZJS-LFIBNONCSA-N
Can. SMILES: COC1=C(C(=CC2=C1N(C=C(C2=O)C(=O)O)C3CC3)F)N4CCC/C(=C(/CN)\F)/C4
InChI: InChI=1S/C21H23F2N3O4/c1-30-20-17-13(19(27)14(21(28)29)10-26(17)12-4-5-12)7-15(22)18(20)25-6-2-3-11(9-25)16(23)8-24/h7,10,12H,2-6,8-9,24H2,1H3,(H,28,29)/b16-11+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/11546234
Guide to Pharmacology: acorafloxacin
Citation:

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