DS-8587

Class: Fluoroquinolone

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Broad spectrum
Institute where first reported:	Daiichi Sankyo
Year first mentioned:	2014
Highest developmental phase:	Phase 1
Development status:	Inactive

Chemical structure(s):
Canonical SMILES:	CC1=C(C(=CC2=C1N(C=C(C2=O)C(=O)O)[C@@H]3C[C@@H]3F)F)N4C[C@]5(CCC[C@]5(C4)N)F
Isomeric SMILES:	CC1=C2C(=CC(=C1N3C[C@@]4(CCC[C@@]4(C3)F)N)F)C(=O)C(=CN2[C@@H]5C[C@@H]5F)C(=O)O
InChI:	InChI=1S/C21H22F3N3O3/c1-10-16-11(18(28)12(19(29)30)7-27(16)15-6-13(15)22)5-14(23)17(10)26-8-20(24)3-2-4-21(20,25)9-26/h5,7,13,15H,2-4,6,8-9,25H2,1H3,(H,29,30)/t13-,15+,20-,21+/m0/s1
InChI Key:	JMXNWTLVUUGTDR-UTQQSMSJSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/56640741

External links:
Guide to Pharmacology:	DS-8587
Citations:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623304/ https://www.ncbi.nlm.nih.gov/pubmed/24594453