Compound ID | 123

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WCK 771

Synonym(s): WCK-771  |  WCK 771

Class: Fluoroquinolone

Agent Type: Synthetic; Small molecule;
Spectrum of activity: Gram-positive
Target Pathogen: Active against pathogen causing hospital-acquired bacterial pneumonia
Combined with other compounds: Yes
Institute where first reported: Wockhardt, India
Year first mentioned: 2001
Highest development stage: Phase 3 (NCT03405064)
Development status: Active
Chemical structure(s):
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Molecular weight: 534.58
Iso. SMILES: C[C@H]1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O.C(C[C@@H](C(=O)O)N)CN=C(N)N
InChI Key: WIFOPRFVQIVWTB-YBVIJTQESA-N
Can. SMILES: C[C@H]1CCC2=C(C(=CC3=C2N1C=C(C3=O)C(=O)O)F)N4CCC(CC4)O.C(C[C@@H](C(=O)O)N)CN=C(N)N
InChI: InChI=1S/C19H21FN2O4.C6H14N4O2/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21;7-4(5(11)12)2-1-3-10-6(8)9/h8-11,23H,2-7H2,1H3,(H,25,26);4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t10-;4-/m00/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9850037
Guide to Pharmacology: levonadifloxacin
Citations:
  • https://aac.asm.org/content/53/2/811
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC529196/
  • https://doi.org/10.1128/aac.48.12.4754-4761.2004

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