Compound ID | 1230

Zidebactam + Cefepime

Synonym(s): WCK 5222  |  WCK-5222  |  WCK5222

Class: Beta-lactam + beta-lactamase inhibitor

Agent Type: Semisynthetic; Small molecule; Direct acting; Antibiotic adjuvant;
Spectrum of activity: Gram-negative
Mechanism of action: Cell wall synthesis inhibitor. Beta-lactamase inhibitor
Target Pathogen: Active against Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii; indicated for complicated urinary tract infections hospital-acquired bacterial pneumonia/ ventilator-associated bacterial pneumonia, complicated intraabdominal infections, and bacteraemia
Combined with other compounds: Yes
Institute where first reported: Wockhardt Ltd.
Highest development stage: Phase 3 (NCT04979806); New Drug Application has been accepted
Development status: Active

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