Compound ID | 1230

Update compound information

Zidebactam + Cefepime

Synonym(s): WCK 5222

Class: Beta-lactam + beta-lactamase inhibitor

Spectrum of activity: Gram-negative
Details of activity: Active against Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii; indicated for complicated urinary tract infections hospital-acquired bacterial pneumonia/ ventilator-associated bacterial pneumonia, complicated intraabdominal infections, and bacteremia
Combined with other compounds: Yes
Institute where first reported: Wockhardt Ltd.
Highest developmental phase: Phase 3 (NCT04979806)
Development status: Active (as of 2024)
External links:
DrugBank link: https://www.drugbank.ca/drugs/DB01413
Guide to Pharmacology: zidebactam
Citations:
  • https://aac.asm.org/content/61/5/e00072-17
  • https://www.business-standard.com/article/news-cm/wockhardt-provides-update-on-its-super-drug-antibiotic-wck-5222-117040300328_1.html
  • https://www.ncbi.nlm.nih.gov/pubmed/28333332
  • https://www.drugbank.ca/drugs/DB13090

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