Compound ID | 124

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Alalevonadifloxacin

Synonym(s): WCK2349

Class: Fluoroquinolone

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: DNA synthesis inhibitor
Target Pathogen: Active against hospital-acquired bacterial pneumonia
Combined with other compounds: Yes
Description: Prodrug of levonadifloxacin
Institute where first reported: Wockhardt, India
Year first mentioned: 2001
Highest development stage: Approved in India
Development status: Approved
Chemical structure(s):
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Molecular weight: 431.46
Iso. SMILES: C[C@H]1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)OC(=O)[C@H](C)N)F)C(=O)O
InChI Key: OUXXDXXQNWKOIF-RYUDHWBXSA-N
Can. SMILES: C[C@H]1CCC2=C(C(=CC3=C2N1C=C(C3=O)C(=O)O)F)N4CCC(CC4)OC(=O)[C@H](C)N
InChI: InChI=1S/C22H26FN3O5/c1-11-3-4-14-18-15(20(27)16(21(28)29)10-26(11)18)9-17(23)19(14)25-7-5-13(6-8-25)31-22(30)12(2)24/h9-13H,3-8,24H2,1-2H3,(H,28,29)/t11-,12-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/16734914
Guide to Pharmacology: alalevonadifloxacin
Citation: http://www.wockhardt.com/pdfs/Press-Release-16-01-2020.pdf

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