Compound ID | 1242
MRX-8
Class: Polymyxin
| Spectrum of activity: | Gram-negative |
| Details of activity: | Disrupts the outer membrane by direct interaction with the lipid A component of the LPS and and disrupts the physical integrity of the phospholipid bilayer of the inner membrane, and possibly additional modes of action. |
| Institute where first reported: | MicuRx |
| Highest developmental phase: | Phase 1 (NCT04649541) |
| Development status: | Active (as of 2024) |
| External links: | |
| Citation: | http://micurxchina.com/project-progress |
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