Compound ID | 1249

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Fosfomycin

Synonym(s): Fosfonomycin  |  Antibiotic 833A

Class: Phosphonic acid antibacterial

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.
Institute where first reported: Zambon Pharmaceutical company
Highest developmental phase: Approved by FDA in 1996
Development status: Approved
Chemical structure(s):
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Molecular weight: 138.06
Iso. SMILES: C[C@H]1[C@H](O1)P(=O)(O)O
InChI Key: YMDXZJFXQJVXBF-STHAYSLISA-N
Can. SMILES: C[C@H]1[C@H](O1)P(=O)(O)O
InChI: InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/446987
Guide to Pharmacology: fosfomycin
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057270/
  • https://www.ncbi.nlm.nih.gov/pubmed/24202878
  • https://www.ncbi.nlm.nih.gov/pubmed/28607025
  • https://www.drugbank.ca/drugs/DB00828

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