Chrysin

Class: Natural flavonoid

Spectrum of activity:	Gram-negative
Details of activity:	H. pylori infections.
Institute where first reported:	Aragon Institute for Health Research (IIS Aragón), Zaragoza, Spain, Department of Biochemistry and Molecular & Cellular Biology, University of Zaragoza, Zaragoza, Spain, Institute for Biocomputation and Physics of Complex Systems & ARAID Foundation, Zaragoza, Spain, Cancer Science Institute, National University of Singapore, Singapore, Singapore, Department of Microbiology, University of Zaragoza & CIBERes, Zaragoza, Spain, Digestive Diseases Service, University Clinic Hospital Lozano Blesa & CIBERehd, Zaragoza, Spain
Highest developmental phase:	Preclinical
Development status:	Active

Chemical structure(s):
Canonical SMILES:	C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O)O)O2
Isomeric SMILES:	C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
InChI:	InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
InChI Key:	RTIXKCRFFJGDFG-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/5281607

External links:
Guide to Pharmacology:	chrysin
Main Source:	https://www.escmid.org/escmid_publications/escmid_elibrary/?q=Small-molecule+inhibitors+of+the+essential+response+regulator+HsrA+exhibit+strong+bactericidal+activity+against+Helicobacter+pylori&id=2173&L=0&x=0&y=0&tx_solr%5Bfilter%5D%5B0%5D=main_filter_eccmid%253Atrue