Compound ID | 1256

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Chrysin

Class: Natural flavonoid

Spectrum of activity: Gram-negative
Details of activity: H. pylori infections.
Institute where first reported: Aragon Institute for Health Research (IIS Aragón), Zaragoza, Spain, Department of Biochemistry and Molecular & Cellular Biology, University of Zaragoza, Zaragoza, Spain, Institute for Biocomputation and Physics of Complex Systems & ARAID Foundation, Zaragoza, Spain, Cancer Science Institute, National University of Singapore, Singapore, Singapore, Department of Microbiology, University of Zaragoza & CIBERes, Zaragoza, Spain, Digestive Diseases Service, University Clinic Hospital Lozano Blesa & CIBERehd, Zaragoza, Spain
Highest development stage: Preclinical
Development status: Active
Chemical structure(s):
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Molecular weight: 254.24
Iso. SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
InChI Key: RTIXKCRFFJGDFG-UHFFFAOYSA-N
Can. SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O)O)O2
InChI: InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/5281607
Guide to Pharmacology: chrysin
Citation: https://www.escmid.org/escmid_publications/escmid_elibrary/?q=Small-molecule+inhibitors+of+the+essential+response+regulator+HsrA+exhibit+strong+bactericidal+activity+against+Helicobacter+pylori&id=2173&L=0&x=0&y=0&tx_solr%5Bfilter%5D%5B0%5D=main_filter_eccmid%253Atrue

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