Kaempferol

Class: Natural flavonoid

Spectrum of activity:	Gram-negative
Details of activity:	H. pylori infections.
Institute where first reported:	Aragon Institute for Health Research (IIS Aragón), Zaragoza, Spain, Department of Biochemistry and Molecular & Cellular Biology, University of Zaragoza, Zaragoza, Spain, Institute for Biocomputation and Physics of Complex Systems & ARAID Foundation, Zaragoza, Spain, Cancer Science Institute, National University of Singapore, Singapore, Singapore, Department of Microbiology, University of Zaragoza & CIBERes, Zaragoza, Spain, Digestive Diseases Service, University Clinic Hospital Lozano Blesa & CIBERehd, Zaragoza, Spain
Highest developmental phase:	Preclinical
Development status:	Active

Chemical structure(s):
Canonical SMILES:	C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O)O)O2)O)O
Isomeric SMILES:	C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
InChI:	InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H
InChI Key:	IYRMWMYZSQPJKC-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/5280863

External links:
Guide to Pharmacology:	kaempferol
Main Source:	https://www.escmid.org/escmid_publications/escmid_elibrary/?q=Small-molecule+inhibitors+of+the+essential+response+regulator+HsrA+exhibit+strong+bactericidal+activity+against+Helicobacter+pylori&id=2173&L=0&x=0&y=0&tx_solr%5Bfilter%5D%5B0%5D=main_filter_eccmid%253Atrue