Hesperetin

Class: Natural flavonoid

Spectrum of activity:	Gram-negative
Details of activity:	H. pylori infections.
Institute where first reported:	Aragon Institute for Health Research (IIS Aragón), Zaragoza, Spain, Department of Biochemistry and Molecular & Cellular Biology, University of Zaragoza, Zaragoza, Spain, Institute for Biocomputation and Physics of Complex Systems & ARAID Foundation, Zaragoza, Spain, Cancer Science Institute, National University of Singapore, Singapore, Singapore, Department of Microbiology, University of Zaragoza & CIBERes, Zaragoza, Spain, Digestive Diseases Service, University Clinic Hospital Lozano Blesa & CIBERehd, Zaragoza, Spain
Highest developmental phase:	Preclinical
Development status:	Active

Chemical structure(s):
Canonical SMILES:	COC1=CC=C(C=C1O)[C@@H]2CC(=O)C3=C(C=C(C=C3O)O)O2
Isomeric SMILES:	COC1=C(C=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)O
InChI:	InChI=1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3/t14-/m0/s1
InChI Key:	AIONOLUJZLIMTK-AWEZNQCLSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/72281

External links:
Guide to Pharmacology:	hesperetin
Main Source:	https://www.escmid.org/escmid_publications/escmid_elibrary/?q=Small-molecule+inhibitors+of+the+essential+response+regulator+HsrA+exhibit+strong+bactericidal+activity+against+Helicobacter+pylori&id=2173&L=0&x=0&y=0&tx_solr%5Bfilter%5D%5B0%5D=main_filter_eccmid%253Atrue