Compound ID | 1259

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Pravibismane

Synonym(s): MBN-101  |  MBN 101  |  MBN101

Class: Membrane-active agent

Agent Type: Synthetic; Small molecule; Direct acting; Antibiofilm;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Membrane-active agent. Disrupts bioenergetics
Institute where first reported: Microbion Corporation
Year first mentioned: 2015
Highest development stage: Phase 2
Development status: Active
Chemical structure(s):
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Molecular weight: 694.52
Iso. SMILES: C1CS[Bi](S1)SCCS[Bi]2SCCS2
InChI Key: GUTNLKRPYCTIHX-UHFFFAOYSA-H
Can. SMILES: C1CS[Bi](S1)SCCS[Bi]2SCCS2
InChI: InChI=1S/3C2H6S2.2Bi/c3*3-1-2-4;;/h3*3-4H,1-2H2;;/q;;;2*+3/p-6
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/10327332
Guide to Pharmacology: pravibismane
Citations:
  • https://doi.org/10.1093/ofid/ofaa439.1472
  • https://doi.org/10.1111/iwj.14817
  • https://microbioncorp.com/pipeline/

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