Compound ID | 126

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MBX-500

Class: Fluoroquinolone

Spectrum of activity: Gram-positive
Details of activity: Clostridium difficile infection (CDI)
Institute where first reported: Microbiotix Inc, USA
Year first mentioned: 2012
Highest developmental phase: Preclinical
Development status: Experimental
Chemical structure(s):
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Molecular weight: 658.76
Iso. SMILES: CCC1=CC(NC2=CC(N(C(N2)=O)CCCCN3CCN(C[C@H]3C)C=4C(C)=CC5=C(C4F)N(C=C(C5=O)C(O)=O)C6CC6)=O)=CC=C1C
InChI Key: YTSQHXVIWZBXIT-HSZRJFAPSA-N
Can. SMILES: CCC1=CC(=CC=C1C)NC2=CC(=O)N(CCCCN3CCN(C[C@H]3C)C4=C(C)C=C5C(=C4F)N(C=C(C5=O)C(=O)O)C6CC6)C(=O)N2
InChI: InChI=1S/C36H43FN6O5/c1-5-24-17-25(9-8-21(24)2)38-29-18-30(44)42(36(48)39-29)13-7-6-12-40-14-15-41(19-23(40)4)32-22(3)16-27-33(31(32)37)43(26-10-11-26)20-28(34(27)45)35(46)47/h8-9,16-18,20,23,26,38H,5-7,10-15,19H2,1-4H3,(H,39,48)(H,46,47)/t23-/m1/s1
External links:
Citations:
  • http://aac.asm.org/content/56/9/4786.full
  • http://aac.asm.org/content/57/8/4039.full
  • https://journals.asm.org/doi/10.1128/aac.00508-12#F1

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