Compound ID | 1269

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Cycloberberine analogue 5b

Class: 13-substituted cycloberberine derivative

Spectrum of activity: Gram-positive
Details of activity: High potency against methicillin-sensitive (MSSA) and resistant strains of S. aureus (MRSA).
Institute where first reported: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, beijing, China
Year first mentioned: 2019
Highest developmental phase: Preclinical
Development status: Active
External links:
Citation: https://www.escmid.org/escmid_publications/escmid_elibrary/?q=Synthesis+and+antibacterial+evaluation+of+13-substituted+cycloberberine+analogues+as+a+novel+class+of+anti-MRSA+agents+target+FtsZ++&id=2173&L=0&x=0&y=0

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