Compound ID | 1289

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Ethyl bromopyruvate

Class: Derivative of 3-bromo-pyruvic acid (3- BPA)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Broad-spectrum antibacterial agent targeting drug-susceptible and -resistant M. tuberculosis and ESKAPE pathogens
Institute where first reported: Department of Biotechnology, National Institute of Pharmaceutical Education and Research; Division of Microbiology, Council of Scientific and Industrial Research-Central Drug Research Institute (CSIR-CDRI); Council of Scientific and Industrial Research-Institute of Microbial Technology (CSIR-IMTECH)
Year first mentioned: 2009
Highest developmental phase: Preclinical
Development status: Active
Chemical structure(s):
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Molecular weight: 195.01
Iso. SMILES: CCOC(=O)C(=O)CBr
InChI Key: VICYTAYPKBLQFB-UHFFFAOYSA-N
Can. SMILES: CCOC(=O)C(=O)CBr
InChI: InChI=1S/C5H7BrO3/c1-2-9-5(8)4(7)3-6/h2-3H2,1H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/66144
Guide to Pharmacology: ethyl bromopyruvate
Citation: https://academic.oup.com/jac/article-abstract/74/4/912/5301660?redirectedFrom=fulltext

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