Compound ID | 1289
Class: Derivative of 3-bromo-pyruvic acid (3- BPA)
Spectrum of activity: | Gram-positive & Gram-negative |
Details of activity: | Broad-spectrum antibacterial agent targeting drug-susceptible and -resistant M. tuberculosis and ESKAPE pathogens |
Institute where first reported: | Department of Biotechnology, National Institute of Pharmaceutical Education and Research; Division of Microbiology, Council of Scientific and Industrial Research-Central Drug Research Institute (CSIR-CDRI); Council of Scientific and Industrial Research-Institute of Microbial Technology (CSIR-IMTECH) |
Year first mentioned: | 2009 |
Highest developmental phase: | Preclinical |
Development status: | Active |
Chemical structure(s): | |
Canonical SMILES: | CCOC(=O)C(=O)CBr |
Isomeric SMILES: | CCOC(=O)C(=O)CBr |
InChI: | InChI=1S/C5H7BrO3/c1-2-9-5(8)4(7)3-6/h2-3H2,1H3 |
InChI Key: | VICYTAYPKBLQFB-UHFFFAOYSA-N |
Structure link: | https://pubchem.ncbi.nlm.nih.gov/compound/66144 |
External links: | |
Guide to Pharmacology: | ethyl bromopyruvate |
Main Source: | https://academic.oup.com/jac/article-abstract/74/4/912/5301660?redirectedFrom=fulltext |