Compound ID | 1291
IARR-Anal10
Class: Antimicrobial peptide
| Agent Type: | Semisynthetic; Direct acting; Antivirulence; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | DNA synthesis inhibitor. Binds to DNA; also suppresses virulence of Klebsiella pneumoniae similar to tigecycline |
| Target Pathogen: | Active against Enterobacteriaceae |
| Description: | Derivate of mBjAMP1 |
| Institute where first reported: | Department of Bioinformatics, Kongju National University; Department of Biomedical Science, Chosun University; Department of Laboratory Medicine, Eulji University-Eulji General Hospital; Department of Internal Medicine, Eulji University-Eulji General Hospital; Department of Infectious Disease, Asan Medical Center, University of Ulsan College of Medicine. |
| Year first mentioned: | 2018 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://doi.org/10.1093/jac/dky144 |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.