Compound ID | 1293
pepR
Class: Antimicrobial peptide (viral-derived peptide)
| Spectrum of activity: | Gram-positive |
| Details of activity: | pepR is able to prevent staphylococcal biofilm formation due to a fast killing of planktonic bacteria, which in turn resulted from a peptide-induced increase in the permeability of the bacterial membranes. |
| Institute where first reported: | Centro de Qu ́ımica-F ́ısica Molecular e IN, Instituto Superior Te ́cnico, Universidade de Lisboa; iBB-Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Te ́cnico, Universidade de Lisboa; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa; Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona Biomedical Research Park; Departamento de Qu ́ımica e Bioqu ́ımica, Faculdade de Cieˆncias, Universidade de Lisboa. |
| Year first mentioned: | 2015 |
| Highest developmental phase: | Preclinical |
| Development status: | Active |
| External links: | |
| Citation: | https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkz223/5498604?searchresult=1 |
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