Compound ID | 1302
Class: Bacterial topoisomerase inhibitor
Spectrum of activity: | Gram-negative |
Details of activity: | The NBTI REDX08106 exhibits potent bactericidal activity against clinically relevant pathogens, which results from its ability to specifically inhibit bacterial type II topoisomerases. Potent antibacterial activity when used to treat A. baumannii-induced mouse thigh infection. |
Institute where first reported: | Redx Pharma; Discuva Ltd; University of Bristol; Glaxosmithkline |
Year first mentioned: | 2017 |
Highest developmental phase: | Preclinical |
Development status: | Active |