Compound ID | 1302

REDX08106

Class: Bacterial topoisomerase inhibitor

Spectrum of activity: Gram-negative
Details of activity: The NBTI REDX08106 exhibits potent bactericidal activity against clinically relevant pathogens, which results from its ability to specifically inhibit bacterial type II topoisomerases. Potent antibacterial activity when used to treat A. baumannii-induced mouse thigh infection.
Institute where first reported: Redx Pharma; Discuva Ltd; University of Bristol; Glaxosmithkline
Year first mentioned: 2017
Highest developmental phase: Preclinical
Development status: Active

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