BVL-GSK098

Synonym(s): Alpibectir

Spectrum of activity:	Gram-positive
Details of activity:	Transcription factor inhibitor/M. tuberculosis
Combined with other compounds:	yes
Institute where first reported:	Bioversys AG
Year first mentioned:	2009
Highest developmental phase:	Phase 1
Development status:	Active

Chemical structure(s):
Canonical SMILES:	C(CC(F)(F)F)C(=O)N1CCC2(CC1)CC(=NO2)C(F)(F)F
Isomeric SMILES:	C1CN(CCC12CC(=NO2)C(F)(F)F)C(=O)CCC(F)(F)F
InChI:	InChI=1S/C12H14F6N2O2/c13-11(14,15)2-1-9(21)20-5-3-10(4-6-20)7-8(19-22-10)12(16,17)18/h1-7H2
InChI Key:	ZEAVKHMQTZBUND-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/137500045

External links:
Guide to Pharmacology:	alpibectir
Main Source:	https://www.imi.europa.eu/projects-results/project-factsheets/tric-tb