Mecillinam

Synonym(s): Amdinocillin

Class: Amidinopenicillin

Spectrum of activity:	Gram-negative
Details of activity:	Low Bioavailability. Used in the treatment of UTI's
Institute where first reported:	Leo Pharmaceutical Products; Roche
Year first mentioned:	1972
Highest developmental phase:	Approved by FDA in 1984
Development status:	Active
Reason Dropped:	Discontinued in US

Chemical structure(s):
Canonical SMILES:	CC1(C)[C@H](C(=O)O)N2C(=O)[C@H]([C@H]2S1)N=CN3CCCCCC3
Isomeric SMILES:	CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)N=CN3CCCCCC3)C(=O)O)C
InChI:	InChI=1S/C15H23N3O3S/c1-15(2)11(14(20)21)18-12(19)10(13(18)22-15)16-9-17-7-5-3-4-6-8-17/h9-11,13H,3-8H2,1-2H3,(H,20,21)/t10-,11+,13-/m1/s1
InChI Key:	BWWVAEOLVKTZFQ-NTZNESFSSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/36273

External links:
Guide to Pharmacology:	mecillinam
Citation:	https://accpjournals.onlinelibrary.wiley.com/doi/abs/10.1002/j.1875-9114.1985.tb04448.x